Endocrine Abstracts

Introduction: Obesity is generally associated with a chronic state of subclinical inflammation. The assessment of the inflammatory status is routinely made by measuring circulating levels of nonspecific proinflammatory markers. Neutrophil to lymphocyte ratio (NRL) is a new simple inflammatory marker which can be reliable in evaluating the inflammatory status occurring in morbidly obese patients. The aim of this study was to investigate the relationship between NLR as an index ...

Aim of the study was to evaluate the relationship between biochemical bone turnover markers, calcium homeostasis parameters and the cardiovascular risk in patients with osteoporosis.Materials and methods: Subjects were 246 patients (mean age of 56.64) diagnosed with osteoporosis referred to the endocrine department of Elias Hospital, between 2009 and 2013, and who agreed with the terms of the study. Data collection consisted of clinica...

Introduction: Primary hepatic neuroendocrine tumours (PHNTs) are a very rare medical entity. Usually, the liver represents the preferential site for metastasis. Large sized, singular nodules are the usual presentation of PHNTs. We report a patient with PHNTs at 4 years of tumour free follow-up.Case presentation: A 45-year-old Caucasian female who presented with nausea, vomiting, diarrhoea, accompanied by diffuse abdominal pain, was found to have on contr...

Introduction: Therapeutic management of clinical nonsecreting pituitary adenomas with ophthalmological manifestations is certainly limited to surgery unless IHC from previous intervention could bring up new data.Case report: A 16-year-old patient was admitted in February 2014 in our Endocrinology Department for short stature (−3.5 S.D.), in the context of an iatrogenic pituitary insufficiency. 7 months before, he had been diagnosed w...

Introduction: Neurofibromatosis type 1 (NF1) is the most common type of NF, and accounts for about 90% of all cases. Primary empty sella syndrome (ESS) results from herniation of arachnoid mater into the pituitary fossa. Since it has been demonstrated that the small anterior pituitary size reflects loss of neurofibromin expression in the hypothalamus, leading to reduced GHRH, pituitary GH and IGF1 production, we agree that IGF1 and GH increased in our patient can be challengin...

Introduction: Central diabetes insipidus is a rare, chronic disease characterized by polyuria and polydipsia due to a partial or total vasopressin deficiency (hypothalamic – neurohypophysial system damage). The aetiology can be familial (autosomal dominant inheritance, X-linked recessive traits; mutation of the vasopressin – neurophysin II genes), secondary (tumours, infections, infiltrative diseases, trauma, vascular lesions) and idiopathic (10–30%).<p clas...

Background: Latent autoimmune diabetes in adults (LADA) is a form of autoimmune diabetes with features overlapping types 1 and 2 diabetes mellitus (T2DM). Frequently patients with LADA could be confound with T2DM patients if it was not performed a glutamic acid decarboxilase antibodies (GADA) evaluation. Even thou LADA and T2DM have similar phenotype, patients with LADA seem to have less frequent macrovascular complications.The aim of the study was to co...

Background: Peripheral neuropathy is the most prevalent chronic complication in diabetes and increases the risk of sarcopenia in these patients. Hand grip strength (HGS) measurement is a good predictor for the presence of sarcopenia.The aim of the study was toevaluate HGS in diabetes patients with and without neuropathy and the clinical and paraclinical parameters that are correlated with HGS.Methods: We evaluated 102 diabetes pati...

Background: Using new technologies, such as glucose sensors and insulin pumps, may help patients with type 1 diabetes mellitus achieve better glycemic control and quality of life. With the occasion of implementing the National Program for free distribution of continuous glucose monitoring systems (CGMS) starting with January 2019, children aged under 13 years were investigated in order to assess the association between previous use of CGMS and insulin pumps and the metabolic c...

Background: Type 1 diabetes is a chronic disease requiring constant management and a disciplined lifestyle, especially in children. Real-time continuous glucose monitoring system (RT-CGMS) can be a useful tool in maintaining good glycemic control. In our medical centre, beginning with January 2019, a National Program for free distribution of RT-CGMS has been set in motion. The results from one of our previous studies indicated a significant increase in glycosylated haemoglobin...